Two New Flavonol Glycosides from Sarcopyramis bodinieri var. delicate

Two new flavonol glycosides from Sarcopyramis bodinieri var. delicate.

Detailed chemical investigation of the herb Sarcopyramis bodinieri var. delicate resulted in the isolation of two new flavonol glycosides, namely, isorhamnetin-3-O-(6''-OE-feruloyl)-beta-D-glucopyranoside (1) and isorhamnetin-3-O-(6''-O-E-feruloyl)-beta-Dgalactopyranoside (2). In addition, four known compounds, quercetin-3-O-(6''-acetyl)-beta-Dglucopyranoside (3), isorhamnetin-3-O-(6''-acetyl)-...

Two New Flavonol Glycosides from Polygala sibirica L. var megalopha Fr.

Two new flavonol glycosides, named polygalin H (1) and polygalin I (2), as well as the known compound polygalin D (3), were isolated from the whole plant of Polygala sibirica L. var megalopha Fr. Their structures were elucidated on the basis of spectroscopic data analysis. These flavonol glycosides exhibited strong inhibitory activities against xanthine oxidase in vitro. Their half-maximal inhi...

Three Sesquiterpene Glycosides from Elsholtzia bodinieri

Two new flavonol glycosides as DNA topoisomerase I poisons.

Flavonoids are secondary plant metabolites whose anticancer properties are actually being studied from an epidemiological and pharmacological point of view. They are believed to be implicated in the lower risk of some forms of cancer observed in Asian countries, due to their capacity to control cell proliferation, to act on certain regulatory enzymes as protein kinases or topoisomerases. Based ...

Flavonol glycosides from Epimedium pubescens.

Five new flavonol glycosides (1, 3, 5-7) were isolated from the aerial parts of Epimedium pubescens Maxim., along with two known compounds, sagittasine C (2) and 4',5-dihydroxyl-8-(3,3-dimethylallyl)-flavonol 3-O-[β-D-xylopyranosyl(1→3)-4-O-acetyl-α-L-rhamnopyranoside]-7-O-β-D-glucopyranoside (4). The structures were elucidated on the basis of their 1D-, 2D-NMR, MS, UV and IR spectra data.